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Administration
Details on system administration tasks such as setup and maintenance of databases and add-ons, user accounts, access rights, and migration and update procedures.
Add-on management
The add-on management feature of PLA 3.0 provides a central interface to activate, deactivate, or remove add-ons. You can request trials or quotes, and view release dates and dependencies, ensuring consistent and version‑controlled functionality across your PLA 3.0 database.
Update add-ons
Keep your add-ons up to date to access the latest improvements in analytical methods and calculations, and to ensure ongoing compatibility with your PLA 3.0 installation.

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Explore PLA 3.0, its key features and ongoing enhancements, and learn how to log in and register.
Key concepts
Learn how the key concepts of PLA 3.0 form the structural foundation for your daily work, supporting method development from initial design to routine production.
Data analysis
Data analysis add-ons offer a wide range of capabilities, ranging from analytical methods over comprehensive analysis to assay workflows and statistical process control.
Data import
Use data acquisition and data import add-ons to import external response values and observation data into PLA 3.0 for further processing and evaluation.
User interface
PLA 3.0 supports you in your daily work by providing a set of graphical and textual user interface elements. Learn about the different elements and how to use them efficiently.
Installation and update
Details on deployment, installation, and update of PLA 3.0, and its initial and advanced setup.
Licensing
Details on the licensing solution of PLA 3.0, the available licensing options, and the activation and management of licenses.
Administration
Details on system administration tasks such as setup and maintenance of databases and add-ons, user accounts, access rights, and migration and update procedures.
- Databases
  Current regulations, such as 21 CFR 11.10 in the pharmaceutical industry, require you to ensure that only authorized individuals can access your systems, perform operations, and sign records. The database-driven approach of PLA 3.0 enables you to take major steps toward meeting these requirements.
- Add-on management
  The add-on management feature of PLA 3.0 provides a central interface to activate, deactivate, or remove add-ons. You can request trials or quotes, and view release dates and dependencies, ensuring consistent and version‑controlled functionality across your PLA 3.0 database.
  - Activate add-ons
    PLA 3.0 add-ons extend the functionality of the PLA 3.0 framework to include the analytical methods your users require and enable them to visualize, document, and report results. To make the functionality of the add-on available for use, you have to activate it in your database.
  - Update add-ons
    Keep your add-ons up to date to access the latest improvements in analytical methods and calculations, and to ensure ongoing compatibility with your PLA 3.0 installation.
  - Download sample data
    For some add-ons, sample documents and templates are available. If you did not download the data when activating the add-on, you can download it from the Add-ons tab.
  - Set up the add-on repository
    By default, each computer running PLA 3.0 hosts its own add-on repository in a default folder. You can change this setup, for example, if you want to set up a central repository.
  - Compatibility matrix
    This compatibility matrix shows which add-ons are compatible with each versions of PLA 3.0. It lists add-ons by category, version, and release year, noting any required dependencies.
- Rights and permissions
  PLA 3.0 provides the features you need to control access to your data in a sophisticated and compliant manner. It combines role-based user rights with resource-based permissions, which enables you to exercise fine-grained control over who can perform particular tasks in a given context and which tasks are allowed with particular data.
- Backup and restore
  To keep the integrity of your PLA 3.0 environment and prevent data loss, we recommend regularly backing up your data. Find details on the key areas to consider and practical guidance on backup and restore procedures within your PLA 3.0 environment.
Regulatory compliance
PLA 3.0 supports you in achieving compliance with regulations such as ISPE GAMP^® 5 and 21 CFR Part 11. It also provides options to validate PLA 3.0 in your environment.
PDF downloads
Download PDF guides of current and previous framework and add-on versions.
Sample lab
Meet the team at Stegmann Labs, where PLA 3.0 plays an essential role in every step of bioassay management.
Glossary
Find definitions of terms.

Update add-ons

Keep your add-ons up to date to access the latest improvements in analytical methods and calculations, and to ensure ongoing compatibility with your PLA 3.0 installation.

About this task

You can update individual add-ons independently of each other and independently of the framework. For details on versioning and updates of add-ons, see the Extensibility topic.

Tip:

You can identify add-ons for which an update is available by the red overlay (

).

Procedure

To update add-ons:

Log in to PLA 3.0.
On the System menu, select Add-on management.
Results: The Add-ons tab opens. You see all add-ons available to you, sorted alphabetically by add-on name.
Note:
Which add-ons are available depends on your information package.
On the Add-ons tab, expand the add-on you want to activate, right-click the required version, and then select Activate.
In the following example, you activate version 27 of the Biological Assay Package.

Figure 1. Add-on update in PLA 3.0
If sample documents and templates are available for the add-on you activate, the Add sample documents and templates dialog opens and displays the respective data. To download the data, complete the following steps:
1. Select the data you want to download.
2. Select a target folder.
3. Select OK, and then select Close.
In the following example, you download sample data for the Dose-Response Analysis Package.

Figure 2. Adding sample data for dose-response analysis

Results

PLA 3.0 adds the add-on to the repository (

) and activates it in the database (

).

What to do next

You can deactivate the older version of the add-on: Right-click the older version, and then select

Deactivate. PLA 3.0 removes the add-on version from the database.