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Administration
Details on system administration tasks such as setup and maintenance of databases and add-ons, user accounts, access rights, and migration and update procedures.
Extensibility with add-ons
PLA 3.0 consists of a framework and add-ons. The PLA 3.0 framework handles data as electronic documents. It provides the features you need to achieve regulatory compliance such as access control, data integrity, security, validation, and traceability.
Activate add-ons
PLA 3.0 add-ons extend the functionality of the PLA 3.0 framework to include the analytical methods your users require and enable them to visualize, document, and report results. To make the functionality of the add-on available for use, you have to activate it in your database.

Get started
Explore PLA 3.0, its key features and ongoing enhancements, and learn how to log in and register.
User interface
PLA 3.0 supports you in your daily work by providing a set of graphical and textual user interface elements. Learn about the different elements and how to use them efficiently.
Key concepts
Details on documents and templates, the data editors and the Content editor of PLA 3.0. Learn about the position factors and data aggregation features.
Data analysis
Data analysis add-ons offer a wide range of capabilities, ranging from analytical methods over comprehensive analysis to statistical process control. PLA 3.0 also provides a set of add-ons that support and supplement data analysis add-ons.
Data import
Use data acquisition and data import add-ons to import external response values and observation data into PLA 3.0 for further processing and evaluation.
Installation
Details on the deployment, installation, initial and advanced setup of PLA 3.0.
Licensing
Details on the licensing solution of PLA 3.0, the available licensing options, and the activation and management of licenses.
Administration
Details on system administration tasks such as setup and maintenance of databases and add-ons, user accounts, access rights, and migration and update procedures.
- Databases
  Current regulations, such as 21 CFR 11.10 in the pharmaceutical industry, require you to ensure that only authorized individuals can access your systems, perform operations, and sign records. The database-driven approach of PLA 3.0 enables you to take major steps toward meeting these requirements.
- Extensibility with add-ons
  PLA 3.0 consists of a framework and add-ons. The PLA 3.0 framework handles data as electronic documents. It provides the features you need to achieve regulatory compliance such as access control, data integrity, security, validation, and traceability.
  - Add-on management
    Manage your existing add-ons from within PLA 3.0 and request trial versions or quotes for add-ons not yet included in your license.
  - Activate add-ons
    PLA 3.0 add-ons extend the functionality of the PLA 3.0 framework to include the analytical methods your users require and enable them to visualize, document, and report results. To make the functionality of the add-on available for use, you have to activate it in your database.
  - Download sample data
    For some add-ons, sample documents and templates are available. If you did not download the data when activating the add-on, you can download it from the Add-ons tab.
  - Set up the add-on repository
    By default, each computer running PLA 3.0 hosts its own add-on repository in a default folder. You can change this setup, for example, if you want to set up a central repository.
- Rights and permissions
  PLA 3.0 provides the features you need to control access to your data in a sophisticated and compliant manner. It combines role-based user rights with resource-based permissions, which enables you to exercise fine-grained control over who can perform particular tasks in a given context and which tasks are allowed with particular data.
- Update, upgrade, and migrate
  Find details on how to update, upgrade or migrate your environment to work with the latest version of PLA 3.0.
Regulatory compliance
PLA 3.0 supports you in achieving compliance with regulations such as ISPE GAMP^® 5 and 21 CFR Part 11. It also provides options to validate PLA 3.0 in your environment.
PDF downloads
Download PDF guides of current and previous framework and add-on versions.
Sample lab
Meet the team at Stegmann Labs, where PLA 3.0 plays an essential role in every step of bioassay management.
Glossary
Find definitions of terms.

Activate add-ons

PLA 3.0 add-ons extend the functionality of the PLA 3.0 framework to include the analytical methods your users require and enable them to visualize, document, and report results. To make the functionality of the add-on available for use, you have to activate it in your database.

About this task

PLA 3.0 add-ons are not activated automatically. Therefore, when you open PLA 3.0 for a newly created database, you see a corresponding information dialog.

Information dialog for activation of add-ons — Figure 1. Information dialog for activation of add-ons

To activate add-ons, you require the Manage add-ons database permission. You can activate any number of add-ons in your database, using the Add-on management feature of PLA 3.0.

Procedure

To activate add-ons:

Log in to PLA 3.0.
On the System menu, select Add-on management.
Result: The Add-ons tab opens.
Note: The tab displays all add-ons available to you, sorted alphabetically by add-on name. Which add-ons are available depends on your information package.
Expand the add-on you want to activate, right-click the required version, and then select Activate.
In the following example, you activate version 26 of the Biological Assay Package.

Figure 2. Add-on activation in PLA 3.0
If sample documents and templates are available for the add-on you activate, the Add sample documents and templates dialog opens and displays the respective data. To download the data, complete the following steps:
1. Select the data you want to download.
2. Select a target folder.
3. Select OK, and then select Close.
In the following example, you download sample data for the Dose-Response Analysis Package.

Figure 3. Adding sample data for dose-response analysis

Result

The add-on is added to the repository (

) and activated in the database (

).

What to do next

Some add-ons require other add-ons to work correctly. For example, to use the Split Assay Package add-on, you also have to activate the Biological Assay Package add-on. If such a dependency exists for an add-on you activated and is not met, the Missing dependencies button is displayed in the status bar. Select this button to find out which additional add-on you have to activate.

How-to video (offline environment)

Activating add-ons in an offline environment requires extra steps. See the following video for details: