Home
Data analysis
Data analysis add-ons offer a wide range of capabilities, ranging from analytical methods over comprehensive analysis to assay workflows and statistical process control.
Supporting add-ons
Find details on add-ons that support and supplement data analysis add-ons.
Measurement Documentation
The Measurement Documentation add-on is a universal add-on for documenting different aspects of a measurement. Its documents can be referenced by other document types, for example, Quantitative response assays.
Operator
Use Operator documents to document the operators involved in the measurement process. Each document represents a single operator.
Work with Operator documents
Use the Content editor to add and edit data about the operator and create links to other documents.

Get started
Get an overview of PLA 3.0, the end-to-end bioassay analysis software. Learn about its ongoing improvements and version updates, and discover the available trial options.
Key concepts
Learn how the key concepts of PLA 3.0 form the structural foundation for your daily work, supporting method development from initial design to routine production.
Data analysis
Data analysis add-ons offer a wide range of capabilities, ranging from analytical methods over comprehensive analysis to assay workflows and statistical process control.
- Biological Assay Package
  Use the Biological Assay Package for potency analysis of biological assays. The add-on comes equipped with a highly flexible test system to qualify your assay. You can perform combination calculations to obtain the reportable value from independent assay runs and use historic assay data to develop equivalence margins.
- bioMérieux Endotoxin Detection Assay Package
  Use the bioMérieux Endotoxin Detection Assay Package add-on to perform endotoxin testing based on recombinant factor C (rFC), a synthetic alternative to naturally sourced reagents derived from horseshoe crabs, as offered by the bioMérieux company.
- Control Chart Package
  The Control Chart Package allows sophisticated statistical process control (for example, by plotting Shewhart I-Charts as recommended in the USP <1010>). It provides visualization options for intervals, subcharts and sidecharts, and allows you to define colors by a secondary characteristic. You can also define rules based on events and time frames.
- Dichotomous Assay Package
  Use the Dichotomous Assay Package to analyze biological assays based on quantal (binary) responses by fitting probit or logit models to estimate the potency of your samples.
- Dose-Response Analysis Package
  The Dose-Response Analysis Package provides various biostatistical methods for immunoassays, ELISA, and more. It supports you in investigating equivalence for calibration curves, provides enhanced data processing, and options for subgroup analysis.
- Microbial Assays for Antibiotics Package
  The Microbial Assays for Antibiotics Package for PLA 3.0 is your software for assessing the potency of antibiotics. This add-on supports various methods, that is, cylinder-plate, turbidimetric, and combination of microbial assays. It enables you to closely follow the guidelines laid out in the United States Pharmacopeia (USP <81>) and the Japanese Pharmacopoeia (JP 4.02).
- Supporting add-ons
  Find details on add-ons that support and supplement data analysis add-ons.
  - Biological Assays Simulation Package
    Use the Biological Assays Simulation Package to create simulations of quantitative response assays (QRAs) and use the Quantitative response assay document type of PLA 3.0 to store the simulated data.
  - Generic Document Types
    Use the Generic Document Types add-on to organize contact-related data, create and manage reminders or internal comments, or streamline workflows where data needs to be consistently organized and referenced.
  - Integration Report Package
    Use the Integration Report Package for creating reports in additional file formats that are not covered by the standard PLA 3.0 reporting functionality. These reports can be used for example for automated processing in third-party software.
  - Measurement Documentation
    The Measurement Documentation add-on is a universal add-on for documenting different aspects of a measurement. Its documents can be referenced by other document types, for example, Quantitative response assays.
    - Installation
      Find details on the system requirements for the Measurement Documentation Package add-on and the steps to install the add-on in your environment.
    - Operator
      Use Operator documents to document the operators involved in the measurement process. Each document represents a single operator.
      - Dashboard
        Use the document dashboard on the right side of the PLA 3.0 main window to get an overview of your document data and view recent changes.
      - Work with Operator documents
        Use the Content editor to add and edit data about the operator and create links to other documents.
    - Equipment
      Use Equipment documents to document the of type of equipment involved in the measurement process. Each document represents a single equipment.
    - Substance
      Use Substance documents to document substances involved in the measurement. Each document represents a single substance.
    - Reference information
      Find reference information on the document types of the Measurement Documentation Package add-on.
  - PLA 3.0 Migration and Archiving Toolkit
    Use the PLA 3.0 Migration and Archiving Toolkit if you are running a PLA 2.0 or PLA 2.1 installation and want to migrate your databases to a PLA 3.0 environment.
  - Split Assay Package
    Use the Split Assay Package to split a Quantitative response assay with several Test and Control samples into individual assays, each with the Standard and one Test or Control sample.
  - Toolkit for Biological Assay Package
    Use the Toolkit for Biological Assay Package to modify the analytical settings of larger sets of Quantitative response assays or split Quantitative response assays with more than one test or control sample into individual assays.
Data import
Use data acquisition and data import add-ons to import external response values and observation data into PLA 3.0 for further processing and evaluation.
User interface
PLA 3.0 supports you in your daily work by providing a set of graphical and textual user interface elements. Learn about the different elements and how to use them efficiently.
Installation and update
Details on deployment, installation, and update of PLA 3.0, and its initial and advanced setup.
Licensing
Details on the licensing solution of PLA 3.0, the available licensing options, and the activation and management of licenses.
Administration
Details on system administration tasks such as setup and maintenance of databases and add-ons, user accounts, access rights, and migration and update procedures.
Regulatory compliance
PLA 3.0 supports you in achieving compliance with regulations such as ISPE GAMP^® 5 and 21 CFR Part 11. It also provides options to validate PLA 3.0 in your environment.
PDF downloads
Download PDF guides of current and previous framework and add-on versions.
Sample lab
Meet the team at Stegmann Labs, where PLA 3.0 plays an essential role in every step of bioassay management.
Glossary
Find definitions of terms.

Work with Operator documents

Use the Content editor to add and edit data about the operator and create links to other documents.

Note: With the Measurement Documentation add-on, you can create links to Contact documents. To do so, you need to activate the Generic Document Types add-on.

Elements and their function

The following figure shows a Operator document displayed in the Content editor of PLA 3.0.

Figure 1. Content editor of an Operator document

Use the Creatable Elements pane to add the elements you require. To edit an existing entry, double-click the element in the Element pane.


Element	Description	Specification	Wiki notation available
Name	The name of the operator.	required	no
Title	The academical title of the operator.	optional	no
Function	The job function or job title of the operator.	optional	no
Department	The department of a company or organization where the operator is located.	optional	no
Phone	Phone type (for example, mobile) and number.	optional, several elements are possible	no
e-Mail	E-Mail type (for example, work) and address.	optional, several elements are possible	no
Contact details	A link to a contact document with full contact details.	optional, several elements are possible	no
Comment	Comments with subject, text, date, author and the possibility to create links to other documents. You can create several text entries and links to other documents in one comment element.	optional, several elements are possible	yes

Tip: For details on the Wiki notation, see the Simplified Wiki notation topic.