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Administration
Details on system administration tasks such as setup and maintenance of databases and add-ons, user accounts, access rights, and migration and update procedures.
Update, upgrade, and migrate
Find details on how to update, upgrade or migrate your environment to work with the latest version of PLA 3.0.
Migrate
Migrate your 2.x assay data to PLA 3.0.
PLA 3.0 Migration and Archiving Toolkit
Use the PLA 3.0 Migration and Archiving Toolkit if you are running a PLA 2.0 or PLA 2.1 installation and want to migrate your databases to a PLA 3.0 environment.
Document types
The add-ons of the PLA 3.0 Migration and Archiving Toolkit provide a set of document types to archive and synchronize your assay data.
PLA 2.x Assay archive document type
The PLA 2.x Assay archive document is the central document of the PLA 3.0 Migration and Archiving Toolkit. It holds all the archived information from a PLA 2.x assay.
Concepts
The PLA 2.x Assay archive document utilizes a set of concepts.

Get started
Explore PLA 3.0, its key features and ongoing enhancements, and learn how to log in and register.
User interface
PLA 3.0 supports you in your daily work by providing a set of graphical and textual user interface elements. Learn about the different elements and how to use them efficiently.
Key concepts
Details on documents and templates, the data editors and the Content editor of PLA 3.0. Learn about the position factors and data aggregation features.
Data analysis
Data analysis add-ons offer a wide range of capabilities, ranging from analytical methods over comprehensive analysis to statistical process control. PLA 3.0 also provides a set of add-ons that support and supplement data analysis add-ons.
Data import
Use data acquisition and data import add-ons to import external response values and observation data into PLA 3.0 for further processing and evaluation.
Installation
Details on the deployment, installation, initial and advanced setup of PLA 3.0.
Licensing
Details on the licensing solution of PLA 3.0, the available licensing options, and the activation and management of licenses.
Administration
Details on system administration tasks such as setup and maintenance of databases and add-ons, user accounts, access rights, and migration and update procedures.
- Databases
  Current regulations, such as 21 CFR 11.10 in the pharmaceutical industry, require you to ensure that only authorized individuals can access your systems, perform operations, and sign records. The database-driven approach of PLA 3.0 enables you to take major steps toward meeting these requirements.
- Extensibility with add-ons
  PLA 3.0 consists of a framework and add-ons. The PLA 3.0 framework handles data as electronic documents. It provides the features you need to achieve regulatory compliance such as access control, data integrity, security, validation, and traceability.
- Rights and permissions
  PLA 3.0 provides the features you need to control access to your data in a sophisticated and compliant manner. It combines role-based user rights with resource-based permissions, which enables you to exercise fine-grained control over who can perform particular tasks in a given context and which tasks are allowed with particular data.
- Update, upgrade, and migrate
  Find details on how to update, upgrade or migrate your environment to work with the latest version of PLA 3.0.
  - Update
    Update your environment to PLA 3.0.7 to benefit from the latest innovations and improvements.
  - Upgrade
    Upgrade from PLA 2.1 or PLA 2.0 to the latest PLA 3.0 version and migrate your assay data.
  - Migrate
    Migrate your 2.x assay data to PLA 3.0.
    - PLA 3.0 Migration and Archiving Toolkit
      Use the PLA 3.0 Migration and Archiving Toolkit if you are running a PLA 2.0 or PLA 2.1 installation and want to migrate your databases to a PLA 3.0 environment.
      - Concepts
        The PLA 3.0 Migration and Archiving Toolkit utilizes a set of concepts that support you in transferring your data from a PLA 2.x source environment to a PLA 3.0 target environment.
      - Add-ons
        The PLA 3.0 Migration and Archiving Toolkit consists of several add-ons that cover different aspects of the archiving and migration process.
      - Document types
        The add-ons of the PLA 3.0 Migration and Archiving Toolkit provide a set of document types to archive and synchronize your assay data.
        PLA 2.x Assay archive document type
        The PLA 2.x Assay archive document is the central document of the PLA 3.0 Migration and Archiving Toolkit. It holds all the archived information from a PLA 2.x assay.
        Concepts
        The PLA 2.x Assay archive document utilizes a set of concepts.
        Dashboard
        The Dashboard of a PLA 2.x Assay archive document gives an overview of the imported PLA 2.x assays. In addition to a graphical display, it also shows basic information about the test results and the potency results.
        PLA 2.x Assay comparison document type
        The PLA 2.x Assay comparison document is the central document type for the comparison process, holding the information of a single assay comparison.
        PLA 2.x Bulk comparison document type
        The PLA 2.x Bulk comparison document can automatically compare a huge number of migrated Quantitative response assays to their original PLA 2.x Assay archive documents.
        PLA 2.x Database synchronization document type
        The PLA 2.x Database synchronization document is the central document type for creating your archive. It holds a list of all synchronized projects and links the PLA 3.0 database to the synchronization folder.
        PLA 2.x Project synchronization document type
        The PLA 2.x Project synchronization document represents the original PLA 2.x project. It holds references to all PLA 2.x Assay archive documents.
      - Work with the Toolkit
        Find details on the steps required to migrate your assay data from PLA versions 2.0 or PLA 2.1 to a PLA 3.0 environment.
      - Installation
        Find details on the installation of the PLA 3.0 Migration and Archiving Toolkit.
      - Reference information
        Find reference information on the document types of the PLA 3.0 Migration and Archiving Toolkit add-on.
Regulatory compliance
PLA 3.0 supports you in achieving compliance with regulations such as ISPE GAMP^® 5 and 21 CFR Part 11. It also provides options to validate PLA 3.0 in your environment.
PDF downloads
Download PDF guides of current and previous framework and add-on versions.
Sample lab
Meet the team at Stegmann Labs, where PLA 3.0 plays an essential role in every step of bioassay management.
Glossary
Find definitions of terms.

Concepts

The PLA 2.x Assay archive document utilizes a set of concepts.

Meta data and data table

The PLA 2.x Assay archive document includes the information that has been extracted from the PLA 2.x Assay document, for example:

Source database information (including the database name, detailed PLA 2.x version number, and date of archiving)
Name of the assay
Assay element structure
Raw data

You can access the raw data using the Content editor:

Figure 1. Observations editor of a PLA 2.x Assay archive document

Note: The data is read-only. However, you can copy it into your clipboard or a spreadsheet program for further processing.

Attachments

The following attachments are available for a PLA 2.x Assay archive document:

All reports registered within your PLA 2.x environment, including all custom reports.
Note: Demo reports (for example, a Word report) have been excluded, as they do not hold sufficient content.
Graphical representations (plots of the curve fits) of the assay elements using the full and the reduced model.
The audit trail entries of the PLA 2.x assay are exported and provided. This allows you to follow up on the history of your assay even after you retired your PLA 2.x environment.
A PSF export file which you can use to reimport the assay into a PLA 2.x installation. PSF is the native file format of PLA 2.x.
Important: You cannot reimport PLA 2.1 assays into PLA 2.0.